UCB gets Japan clearance for two new drugs






BRUSSELS (Reuters) – Belgian pharmaceutical company UCB has secured two regulatory clearances in Japan, further cementing its worldwide shift to a new generation of drugs.


The company said in a statement on Tuesday that the Japanese Ministry of Health, Labour and Welfare had approved UCB’s Neupro patch to treat Parkinson’s disease and moderate-to-severe Restleg Legs Syndrome in adults.






Otsuka Pharmaceutical has the exclusive rights for developing and marketing Neupro in Japan, with UCB responsible in all other regions worldwide. Neupro is available in 35 countries.


In a separate statement on Tuesday, UCB said its drug Cimzia had been approved in Japan for treatment of rheumatoid arthritis in adults.


UCB is jointly developing the drug there with Astellas Pharma Inc, with UCB manufacturing it and Astellas managing distribution and sales. UCB said it would receive an unspecified milestone payment from Astellas.


Cimzia is currently being sold in over 30 countries, including the United States and in Europe.


UCB, a central nervous system and immunology specialist, is placing its hopes on three new drugs – Cimzia, Neupro and epilepsy treatment Vimpat – as previous blockbuster Keppra, also for epilepsy, faces patent expiries.


(Reporting by Philip Blenkinsop; editing by Patrick Graham)


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Former South African president Mandela “much better”: Zuma






JOHANNESBURG (Reuters) – Former South African president and anti-apartheid hero Nelson Mandela is looking much better after more than two weeks in hospital, President Jacob Zuma said on Tuesday.


Zuma, who visited Mandela on Christmas Day, said in a statement that doctors were happy with the progress the elder statesman was making.






“We found him in good spirits. He was happy to have visitors on this special day and is looking much better. The doctors are happy with the progress that he is making,” said Zuma.


The 94-year-old Nobel Peace laureate has been in hospital in Pretoria for more than two weeks after being admitted for routine tests and then undergoing surgery to remove gallstones.


Zuma, who has just been re-elected as president of the ruling African National Congress party, last week described Mandela’s condition as serious. Periodic statements from the presidency continue to stress that the veteran politician is responding to treatment.


No date has been given for his release from hospital. Mandela, who is internationally admired for his struggle against minority white rule, retired from public life in 2004 after serving one term as South Africa‘s first black president.


(Reporting by Sherilee Lakmidas; Editing by Andrew Osborn)


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Winter storms, tornado threats for Christmas in US


NEW ORLEANS (AP) — Forecasts of snow, sleet and freezing rain threatened to complicate Christmas Day travel around the nation's midsection Tuesday as several Gulf Coast states braced for a chance of twisters and powerful thunderstorms.


A blizzard watch was posted for parts of Indiana and western Kentucky for storms expected to develop Tuesday amid predictions of up to 4 to 7 inches of snow in coming hours. Much of Oklahoma and Arkansas braced under a winter storm warning of an early mix of rain and sleet later turning to snow.


Some mountainous areas of Arkansas' Ozark Mountains could get up to 10 inches of snow amid warnings travel could become "very hazardous or impossible" in the northern tier of the state from near whiteout conditions, the National Weather Service said.


Early Tuesday, the Oklahoma Department of Public Safety said some bridges and overpasses were already becoming slick. Also, Kathleen O'Shea with Oklahoma Gas and Electric said the utility was tracking the storm system to see where repair crews might be needed among nearly 800,000 customers in Oklahoma and western Arkansas.


Elsewhere, areas of east Texas and Louisiana braced for possible thunderstorms as forecasters eyed a swath of the Gulf Coast from east Texas to the Florida Panhandle for the threat of any tornadoes.


Storms expected during the day Tuesday along the Gulf Coast could bring strong tornadoes or winds of more than 75 mph, heavy rain, quarter-sized hail and dangerous lightning in Louisiana and Mississippi, the weather service said.


"Please plan now for how you will receive a severe weather warning, and know where you will go when it is issued. It only takes a few minutes, and it will help everyone have a safe Christmas," Mississippi Gov. Phil Bryant said.


Ten storm systems in the last 50 years have spawned at least one Christmastime tornado with winds of 113 mph or more in the South, said Chris Vaccaro, a National Weather Service spokesman in Washington, via email.


The most lethal were the storms of Dec. 24-26, 1982, when 29 tornadoes in Oklahoma, Missouri, Arkansas, Tennessee and Mississippi killed three people and injured 32; and those of Dec. 24-25, 1964, when two people were killed and about 30 people injured by 14 tornadoes in seven states.


In Alabama, the director of the Emergency Management Agency, Art Faulkner, said he has briefed both local officials and Gov. Robert Bentley on plans for dealing with a possible outbreak of storms.


No day is good for severe weather, but Faulkner said Christmas adds extra challenges because people are visiting unfamiliar areas and often thinking more of snow than possible twisters.


"We are trying to get the word out through our media partners and through social media that people need to be prepared," Faulkner said


During the night, flog blanketed highways at times in the Southeast, including arteries in Atlanta where motorists slowed as a precaution. Fog advisories were posted from Alabama through the Carolinas into southwestern Virginia.


Several communities in Louisiana went ahead with the annual Christmas Eve lighting more than 100 towering log teepees for annual bonfires to welcome Pere Noel along the Mississippi River between New Orleans and Baton Rouge. That decision came after fire chiefs and local officials decided to go ahead with the tradition after an afternoon conference call with the National Weather Service.


In California, after a brief reprieve across the northern half of the state on Monday, wet weather was expected to make another appearance on Christmas Day. Flooding and snarled holiday traffic were expected in Southern California.


___


Associated Press writer Bob Johnson in Montgomery, Ala., and Ken Miller in Oklahoma City, Okla., contributed to this report.


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New Zealand level series thanks to Guptill century






EAST LONDON, South Africa (Reuters) – A brilliant, unbeaten century from opener Martin Guptill led New Zealand to an eight-wicket victory off the final ball against South Africa in the second T20 international on Sunday.


Chasing 169 for victory in 19 overs at Buffalo Park, Guptill helped erase the memory of Friday’s embarrassing capitulation to 86 all out in Durban with a stunning batting display as the tourists reached their target for the loss of just two wickets to level the series 1-1.






Requiring 39 from the final four overs and 11 off the last, Guptill was on 97 and needing four for victory when Rory Kleinveldt bowled the final delivery – a low full toss which was eased away through extra cover.


Guptill’s unbeaten 101 was just the third T20 international century by a New Zealander, the first two belonging to captain Brendon McCullum who was almost anonymous with 17 from 15 balls during a second-wicket partnership of 73 with Guptill.


The right-handed opener was similarly dominant during an opening stand of 76 with Rob Nicol (25) as he drove the Proteas attack impeccably straight and displayed the skills – and patience – so obviously missing from the New Zealand batsman in Durban.


Captain Faf du Plessis led from the front once again as South Africa posted a competitive 165-5 in 19 overs after losing the toss and being asked to bat first.


Du Plessis paced his innings to perfection on a tricky pitch to reach 63 from 43 balls with eight fours and a six in a match reduced to 19 overs per side following a 52-minute floodlight failure.


The deciding match takes place in Port Elizabeth on Wednesday.


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Atheist Kids and Bullying: Just an Xbox and a Football Game Away From Redemption






I’ll never forget the year my eight-year-old daughter came home from school saying she got in trouble for going to the bathroom.


“I was afraid,” she said, “that the devil was coming out of the mirror to get me…. I wanted Aya to stay with me until I was done.”






Like any parent, I sat her down and asked her to tell me why she would ever think a mirror could spawn something as terrifying as that.


“Susie told me because I didn’t believe in god, the devil was coming to take my soul.”


MORE: Bullying the Bullies: What to Do to Save the Next Amanda Todd


“Susie” as we’ll call her, was a fellow eight-year-old student at my daughter’s Catholic school. Susie attended church every Sunday with her family—the same church that many of her classmates to this day all go to.


Was my daughter being bullied for being an atheist? I quickly dismissed it. After all, these were only eight-year-old girls, and it wasn’t like we talked about god hating with our morning cereal.


I soon noticed a new pattern of my daughter: She wouldn’t enter a bathroom without a friend or parent and began wetting the bed at night for fear of our extensive collection of bathroom mirrors pulling her into almighty hell at 2 a.m.


Sure enough, the religious eight-year-old was still pressuring my daughter to consider her morality, spirituality and reason for living daily in the school bathroom.


“When the child goes to school, and encounters for the first time other kids who don’t believe the same thing, whether it’s no belief or a different belief system, that can rock a kid’s world.”


I got on the phone and made sure the principal was aware of the bullying, that the child was reported and that my daughter would hopefully make the choice not to play with her anymore. The school thought I was a little crazy. Bullying was getting punched in the stomach in a dark place behind the school, not a little girl being taunted for not believing she was going to have life eternal. This was a new place they were afraid to gain control of. The principal, a former nun, kept a tight lip.


According to the American Society for the Prevention of Cruelty to Children, every day “an estimated 160,000 students in the U.S. refuse to go to school because they dread the physical and verbal aggression of their peers. Many more attend school in a chronic state of anxiety and depression.”


Courtney Campbell, Professor of Religion and Culture at Oregon State University, says he encountered the same case with his own children who were told at a very early age by some of their “friends” that they were “going to hell.” Though there were no physical beatings, the “psychic bullying” may have been worse.


“There is a phenomenon of religious-bullying at an early age, though in my own view/experience with raising my kids, it’s less of an issue than lookism [obese kids], size [‘big’ bullies], or gender, or clothes, or any of a number of things that kids do to manifest power over others,” says Campbell.


He points out that in most conservative/evangelical/fundamentalist Christian traditions, kids are taught at a very early age in their Sunday schools or summer bible camps that there’s only one path to happiness and salvation. That teaching, absorbed at a young age, is on its own rather threatening to the child.


“When the child goes to school, and encounters for the first time other kids who don’t believe the same thing, whether it’s no belief or a different belief system, that can rock a kid’s world,” Campbell adds.


Blame it on fear, maybe a calling out of one’s most sacred and learned family beleifs, but this form of push and shove is only getting more sophisticated.


Rachel Wagner, Associate Professor for the Department of Philosophy and Religion at Ithaca College and author of Godwired: Religion, Ritual and Virtual Reality, says we are overlooking a major player of the religious bullying model—video games.


“If we compare video games to rituals as similar kinds of interactive experiences that are meant to shape how we see ourselves and others in the world, then we can argue something more basic—that video games (like rituals) can teach people habits of encounter—and offer youth deeply problematic models of encounter with difference,” says Wagner, who adds that in her next book, she’ll argue that religion has always had the ability to be “played” like a game, a religious encounter she coins “shooter religion.”


While Wagner admits it’s very important to remember that all world religions also have “deep and abiding practices urging compassion, understanding, tolerance, and social justice,” in today’s media-soaked society, feeling the need to retreat into a simpler world where people can be reduced to camps can be terribly tempting.


Stacy Pershall, author of Loud in the House of Myself: Memoir of a Strange Girl, says that growing up in Prairie Grove, Arkansas, in an athletics-focused, Christian bible belt, she was used to being surrounded by “Jesus talk.”


Pershall, who was bullied for being a “strange girl,” when young, unathletic and atheist to boot, now works and empowers high school and college students as a writing teacher and mental health speaker.


“Although it still makes my heart pound a little to stand in front of a crowd and admit that I don’t believe in god (as I recently did at Catholic University in D.C.), somebody needs to do it. I get to be the adult who says to kids, ‘I’m an atheist, I have morals, I have friends, I’m happy, and I care about how you feel.’ That’s a wonderful, powerful thing. I get to tell bullied kids who might be considering suicide that they’re not alone, and that they have kindred spirits. It’s what the Flying Spaghetti Monster put me on Earth to do.”


Were you ever bullied? Leave what you were bullied about in COMMENTS.


These are solely the author’s opinions and do not represent those of TakePart, LLC or its affiliates.


Related Stories on TakePart:


• 5 Things to Keep in Mind About Bullying


• A Bully’s Paradise: Hidden Halls, Dark Corners and No Supervision


• Mother Bullied to Abort Unborn Twins?



Amy DuFault is a writer and editor whose work has been published in EcoSalon, Huffington Post, Ecouterre, Organic Spa, Coastal Living, Yahoo!, The Frisky and other online and print publications. In addition to being a former co-owner of an eco-boutique, she coaches and connects the sustainable fashion community to feed her soul. She also dreams of singing in an all-girl punk band even though she has stage fright. @amytropolis | TakePart.com


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Pro-gun rights US petition to deport Piers Morgan






LONDON (AP) — Tens of thousands of people have signed a petition calling for British CNN host Piers Morgan to be deported from the U.S. over his gun control views.


Morgan has taken an aggressive stand for tighter U.S. gun laws in the wake of the Newtown, Connecticut, school shooting. Last week, he called a gun advocate appearing on his “Piers Morgan Tonight” show an “unbelievably stupid man.”






Now, gun rights activists are fighting back. A petition created Dec. 21 on the White House e-petition website by a user in Texas accuses Morgan of engaging in a “hostile attack against the U.S. Constitution” by targeting the Second Amendment. It demands he be deported immediately for “exploiting his position as a national network television host to stage attacks against the rights of American citizens.”


The petition has already hit the 25,000 signature threshold to get a White House response. By Monday, it had 31,813 signatures.


Morgan seemed unfazed — and even amused — by the movement.


In a series of Twitter messages, he alternately urged his followers to sign the petition and in response to one article about the petition said “bring it on” as he appeared to track the petition’s progress.


“If I do get deported from America for wanting fewer gun murders, are there any other countries that will have me?” he wrote.


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FDA warns doctors of counterfeit Botox






WASHINGTON (AP) — Federal regulators have warned more than 350 medical practices that Botox they may have received from a Canadian supplier is unapproved and could be counterfeit or unsafe.


The Food and Drug Administration said in a letter sent last month, a letter released publicly last week, that batches of the wrinkle treatment shipped by suppliers owned by pharmacy Canada Drugs have not been approved by the FDA and that the agency cannot assure their effectiveness or their safety.






The FDA said Canada Drugs was previously tied to shipping unapproved and counterfeit cancer drugs.


The agency warned doctors about buying drugs from sources other than licensed U.S. pharmacies. It is the fifth warning the agency has made this year about foreign suppliers providing unapproved drugs.


In February, the agency warned 19 medical practices that they had received a counterfeit version of the cancer drug Avastin. On three more occasions the FDA issued similar warnings about counterfeit Avastin and Altuzan, another brand name for the same drug. The alerts were also primarily targeted at drugs distributed by Canada Drugs.


A request for comment from the drug distributor was not immediately returned.


Drug shortages increased the financial incentives for some pharmacies to provide counterfeit or illegally imported drugs. The drugs subject to warnings have all been injectable treatments typically distributed through medical practices and not directly to patients.


In October, the FDA ordered operators of about 4,100 websites to immediately stop selling unapproved medications to U.S. consumers. The vast majority of those sites were operated by Canada Drugs. The site was still operating Friday.


Genuine Botox is made by Allergan Inc., based in Irvine, Calif. Avastin is made by Roche Holding AG’s Genentech unit.


___


Online:


The FDA’s warning letter, plus a list of doctors who received it: http://1.usa.gov/R7jKiR


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Snow threatens post-Christmas travel




A huge storm that dumped heavy snow and rain on the West Coast is
expected to move east and could spoil travel plans for people looking to
return home the day after Christmas, which is considered one of the
busiest travel days.

The powerful storm that has already blanketed much of Northern California is expected to move east over the next few days and drop snow from Oklahoma starting today before finishing up in the Northeast sometime Wednesday.



The Midwest will be covered with snow by Wednesday, likely causing delays at major airports in cities including Cleveland, Detroit, St. Louis and Chicago just in time for post-Christmas travel, when millions of Americans will be on the move.



Snow could arrive in the Northeast by Thursday, dropping 1-3 inches over parts of New England.



In Syracuse, N.Y., plows are working overtime, dealing with two consecutive days of snow this weekend during the city's first snowstorm of the season. As the city continues to dig out, all eyes are watching the storm roll in from the west.



Torrential rain and heavy winds have also caused trouble for California's Bay Area over the weekend, which has seen severe flooding, power outages and delays for those planning to fly out for the holidays.



Ryan Damstra of Northern California spent seven hours at San Francisco's International Airport Sunday but was not able to fly.



"After I found out my flight had been canceled after four hours of waiting in the airport, I had to wait another three hour customer service line," Damstra told ABC News Radio.



More than 400 flights were canceled on Sunday at San Francisco International Airport. Travelers had to deal with more than 200 cancelations on Saturday.



So far this month San Francisco got almost five inches of rain that is almost twice as much as they get for the entire month of December.



Severe snow and rain are not the only issues facing Americans looking to get home before the New Year. Several states in the Gulf of Mexico all the way from Houston to Raleigh, N.C., are bracing for possible tornadoes starting today and lasting until Wednesday.



The biggest chance for tornadoes will be tomorrow from Houston to New Orleans to Birmingham and Atlanta.



AAA predicts 93.3 million people will travel more than 50 miles this holiday season, from Saturday through New Year's Day. That's a 1.6 percent increase from last year. Christmas is the third-busiest holiday for travelers, after Memorial Day and Thanksgiving.



AAA is urging drivers to leave earlier or later to dodge bad weather.



ABC News' Max Golembo contributed to this report.

Also Read

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Atheist Kids and Bullying: Just an Xbox and a Football Game Away From Redemption






I’ll never forget the year my eight-year-old daughter came home from school saying she got in trouble for going to the bathroom.


“I was afraid,” she said, “that the devil was coming out of the mirror to get me…. I wanted Aya to stay with me until I was done.”






Like any parent, I sat her down and asked her to tell me why she would ever think a mirror could spawn something as terrifying as that.


“Susie told me because I didn’t believe in god, the devil was coming to take my soul.”


MORE: Bullying the Bullies: What to Do to Save the Next Amanda Todd


“Susie” as we’ll call her, was a fellow eight-year-old student at my daughter’s Catholic school. Susie attended church every Sunday with her family—the same church that many of her classmates to this day all go to.


Was my daughter being bullied for being an atheist? I quickly dismissed it. After all, these were only eight-year-old girls, and it wasn’t like we talked about god hating with our morning cereal.


I soon noticed a new pattern of my daughter: She wouldn’t enter a bathroom without a friend or parent and began wetting the bed at night for fear of our extensive collection of bathroom mirrors pulling her into almighty hell at 2 a.m.


Sure enough, the religious eight-year-old was still pressuring my daughter to consider her morality, spirituality and reason for living daily in the school bathroom.


“When the child goes to school, and encounters for the first time other kids who don’t believe the same thing, whether it’s no belief or a different belief system, that can rock a kid’s world.”


I got on the phone and made sure the principal was aware of the bullying, that the child was reported and that my daughter would hopefully make the choice not to play with her anymore. The school thought I was a little crazy. Bullying was getting punched in the stomach in a dark place behind the school, not a little girl being taunted for not believing she was going to have life eternal. This was a new place they were afraid to gain control of. The principal, a former nun, kept a tight lip.


According to the American Society for the Prevention of Cruelty to Children, every day “an estimated 160,000 students in the U.S. refuse to go to school because they dread the physical and verbal aggression of their peers. Many more attend school in a chronic state of anxiety and depression.”


Courtney Campbell, Professor of Religion and Culture at Oregon State University, says he encountered the same case with his own children who were told at a very early age by some of their “friends” that they were “going to hell.” Though there were no physical beatings, the “psychic bullying” may have been worse.


“There is a phenomenon of religious-bullying at an early age, though in my own view/experience with raising my kids, it’s less of an issue than lookism [obese kids], size [‘big’ bullies], or gender, or clothes, or any of a number of things that kids do to manifest power over others,” says Campbell.


He points out that in most conservative/evangelical/fundamentalist Christian traditions, kids are taught at a very early age in their Sunday schools or summer bible camps that there’s only one path to happiness and salvation. That teaching, absorbed at a young age, is on its own rather threatening to the child.


“When the child goes to school, and encounters for the first time other kids who don’t believe the same thing, whether it’s no belief or a different belief system, that can rock a kid’s world,” Campbell adds.


Blame it on fear, maybe a calling out of one’s most sacred and learned family beleifs, but this form of push and shove is only getting more sophisticated.


Rachel Wagner, Associate Professor for the Department of Philosophy and Religion at Ithaca College and author of Godwired: Religion, Ritual and Virtual Reality, says we are overlooking a major player of the religious bullying model—video games.


“If we compare video games to rituals as similar kinds of interactive experiences that are meant to shape how we see ourselves and others in the world, then we can argue something more basic—that video games (like rituals) can teach people habits of encounter—and offer youth deeply problematic models of encounter with difference,” says Wagner, who adds that in her next book, she’ll argue that religion has always had the ability to be “played” like a game, a religious encounter she coins “shooter religion.”


While Wagner admits it’s very important to remember that all world religions also have “deep and abiding practices urging compassion, understanding, tolerance, and social justice,” in today’s media-soaked society, feeling the need to retreat into a simpler world where people can be reduced to camps can be terribly tempting.


Stacy Pershall, author of Loud in the House of Myself: Memoir of a Strange Girl, says that growing up in Prairie Grove, Arkansas, in an athletics-focused, Christian bible belt, she was used to being surrounded by “Jesus talk.”


Pershall, who was bullied for being a “strange girl,” when young, unathletic and atheist to boot, now works and empowers high school and college students as a writing teacher and mental health speaker.


“Although it still makes my heart pound a little to stand in front of a crowd and admit that I don’t believe in god (as I recently did at Catholic University in D.C.), somebody needs to do it. I get to be the adult who says to kids, ‘I’m an atheist, I have morals, I have friends, I’m happy, and I care about how you feel.’ That’s a wonderful, powerful thing. I get to tell bullied kids who might be considering suicide that they’re not alone, and that they have kindred spirits. It’s what the Flying Spaghetti Monster put me on Earth to do.”


Were you ever bullied? Leave what you were bullied about in COMMENTS.


These are solely the author’s opinions and do not represent those of TakePart, LLC or its affiliates.


Related Stories on TakePart:


• 5 Things to Keep in Mind About Bullying


• A Bully’s Paradise: Hidden Halls, Dark Corners and No Supervision


• Mother Bullied to Abort Unborn Twins?



Amy DuFault is a writer and editor whose work has been published in EcoSalon, Huffington Post, Ecouterre, Organic Spa, Coastal Living, Yahoo!, The Frisky and other online and print publications. In addition to being a former co-owner of an eco-boutique, she coaches and connects the sustainable fashion community to feed her soul. She also dreams of singing in an all-girl punk band even though she has stage fright. @amytropolis | TakePart.com


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New Zealand level series thanks to Guptill century






EAST LONDON, South Africa (Reuters) – A brilliant, unbeaten century from opener Martin Guptill led New Zealand to an eight-wicket victory off the final ball against South Africa in the second T20 international on Sunday.


Chasing 169 for victory in 19 overs at Buffalo Park, Guptill helped erase the memory of Friday’s embarrassing capitulation to 86 all out in Durban with a stunning batting display as the tourists reached their target for the loss of just two wickets to level the series 1-1.






Requiring 39 from the final four overs and 11 off the last, Guptill was on 97 and needing four for victory when Rory Kleinveldt bowled the final delivery – a low full toss which was eased away through extra cover.


Guptill’s unbeaten 101 was just the third T20 international century by a New Zealander, the first two belonging to captain Brendon McCullum who was almost anonymous with 17 from 15 balls during a second-wicket partnership of 73 with Guptill.


The right-handed opener was similarly dominant during an opening stand of 76 with Rob Nicol (25) as he drove the Proteas attack impeccably straight and displayed the skills – and patience – so obviously missing from the New Zealand batsman in Durban.


Captain Faf du Plessis led from the front once again as South Africa posted a competitive 165-5 in 19 overs after losing the toss and being asked to bat first.


Du Plessis paced his innings to perfection on a tricky pitch to reach 63 from 43 balls with eight fours and a six in a match reduced to 19 overs per side following a 52-minute floodlight failure.


The deciding match takes place in Port Elizabeth on Wednesday.


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